LungSphereLS

Respiratory technology · In development

Transforming Inhalation.
Rethinking Respiratory Health.

LungSphere is developing a new nicotine-free inhalation platform designed to bridge the gap between human behaviour and respiratory care.

01 — The Problem

Two persistent challenges at the intersection of behaviour and the lungs.

Smoking cessation remains difficult

Many people who want to stop smoking find it hard to do so. Existing approaches often address nicotine dependence without fully engaging the habitual and sensory aspects of inhalation.

Inhaled therapy depends on the user

Respiratory treatments rely on correct inhaler technique and consistent use. Usability and adherence can limit how well inhaled medicines perform in everyday life.

02 — Our Approach

A developing platform built on three principles.

A more engaging inhalation experience

Designing an experience that respects the behavioural and sensory side of inhalation, not only the pharmacology.

Controlled aerosol generation and airflow

Pursuing precise, repeatable control over how an aerosol is formed and carried with each breath.

Future respiratory drug delivery

Exploring whether the same platform could one day support delivery of therapeutic formulations to the lungs.

These are development goals. They have not been demonstrated in clinical studies.

03 — The Technology

Where aerosol science, airflow and formulation meet.

Conceptual illustration of mist particles entering the lungs through the branching airways
01

Aerosol generation

Forming an aerosol with consistent, well-characterised properties.

02

Airflow control

Shaping how air and aerosol move together through each inhalation.

03

Formulation research

Screening and evaluating formulations designed alongside the device.

Technical specifics remain confidential while development continues.

Current concept · In development

From airflow science to a device you can hold.

The LungSphere concept brings these principles together in a compact, nicotine-free handheld form.

Nicotine-free

Designed around the inhalation experience itself — no nicotine involved.

Detachable mouthpiece

A removable cap protecting the airway inlet between uses.

Dose display

A simple readout of remaining doses, supporting consistent use.

One-hand form

Shaped to sit naturally in the hand during inhalation.

The device is under development. These images show the current concept — it is not a clinically validated or commercially available product.

LungSphere handheld device concept with its detachable mouthpieceLungSphere device concept held in one hand

04 — Development Journey

An honest roadmap from concept to potential application.

  1. Engineering proof of concept

    In progress
  2. Formulation screening and preclinical evaluation

    In progress
  3. Integration of device and formulation

    Planned
  4. Future evaluation of therapeutic applications

    Future ambition

05 — Our Vision

A platform for research today and, potentially, therapy tomorrow.

Our long-term ambition is to build an inhalation platform that could first support research into smoking replacement — exploring whether a carefully designed inhalation experience can help address the behavioural side of smoking.

In the future, the same foundations in aerosol and airflow control could potentially enable respiratory drug delivery. Each step will be guided by rigorous science and appropriate regulatory pathways.

06 — Team

The People Behind LungSphere.

Portrait of Zaid Elhusseini, Ph.D.

Zaid Elhusseini, Ph.D.

Founder & CEO

Respiratory scientist with expertise in pulmonary pathology and translational health.

Current
Imperial College London
Previous
Harvard Medical School · University of Groningen
Portrait of Yehya Al-Adwi, Ph.D.

Yehya Al-Adwi, Ph.D.

Co-Founder & CSO

Pharmacist and translational scientist specialising in lung inflammation and fibrosis.

Current
QPS Netherlands
Previous
University of Groningen
Portrait of Wael Itani, Ph.D.

Wael Itani, Ph.D.

Engineering Collaborator

Specialising in the design and modelling of thermal-fluid systems for medical devices.

Current
American University of Beirut
Previous
New York University · Shanghai Jiao Tong University

07 — Contact

Let's Rethink Respiratory Health.

We welcome conversations with research collaborators, strategic partners and investors who share our interest in the future of inhalation.

contact@lungsphere.co.uk